The Genome Assembly and Annotation Team utilizes the latest technology and applies state-of-the art methods to assemble and annotate genomes. Collaborate with us!
The team assembles genomes of species across all domains of life, from large eukaryotic genomes and transcriptomes, especially those of animals and plants, to the tiniest bacteria. Other types of genomes analyzed include those of organelles, endosymbionts, metagenomes and metatranscriptomes, and cancer genomes. Genome assembly is not only difficult due to the sheer size of the data and computational requirements, but also because the biology of genomes is confounded by repetitive elements, polyploidy and variation (single-nucleotide, insertions/deletions, and larger structural variants). The team focuses its efforts on meeting and overcoming these challenges, incorporating new technologies and developing new computational protocols as each project demands.
Annotation of the gene content of the newly assembled genome is key to understanding the genome, once finished. On this front the teams has made progress in developing a rapid robust annotation pipeline, significantly cutting down the time required to annotate a genome.
